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Israeli VC firm Pitango raises $300m for new funds

Pitango Venture Capital has secured US$300 million for two new funds targeting seed-stage startups.

The Israeli firm, which manages over US$3 billion in assets, split the capital evenly between Pitango First, focused on early-stage tech startups, and Pitango HealthTech, which invests in life sciences companies.

Pitango First is led by Eyal Niv, Dr. Ayal Itzkovitz, Gad Huldai, and Yair Cassuto, and has already invested in firms such as AAI, Gamma Time, and Apprentice.AI across sectors like AI, quantum, and cybersecurity.

Pitango HealthTech, headed by Ittai Harel, Hila Karah, and Dr. Jonathan Glazer, backs startups in digital medicine, medical devices, and biopharma, and has invested in companies including QuantHealth and Guardoc.

Founded in 1993, Pitango counts both Israeli and international financial institutions among its investors.

🔗 Source: Calcalist

🧠 Food for thought

Implications, context, and why it matters.

Fund deployment hints at focus

  • Each fund has US$150 million. Listed checks start at US$5 million 1. That mix supports 15 to 25 core positions with larger stakes. Managers hold back 40 to 50% for follow-on rounds (additional financing after the initial check). This rejects high-volume small-check seed plays.
  • The firm runs three focused pools, Pitango First for early-stage, Pitango Growth for later rounds, and Pitango HealthTech 2. This structure funds follow-ons in house as companies mature and lowers reliance on outside syndicates.
  • More than 90 exits came via NASDAQ or NYSE listings 2. Others came from sales to Google or Apple 2. More buyers included IBM or Cisco 2. Sources do not share Total Value to Paid-In (TVPI) for prior Pitango First and HealthTech funds, so limited partners lack benchmarks to weigh the US$300 million risk.

B2B vendors can pitch newly funded portfolio firms

  • Cloud infrastructure firms and AI toolmakers can map Pitango First’s bets 2. Security vendors can track activity in AI, quantum computing, and cybersecurity. Recent adds include AAI and Apprentice.AI. Pitch developer tools (dev tools), model-training platforms, or zero-trust security as portfolio engineering teams grow.
  • HealthTech service providers can pitch Pitango HealthTech’s companies in digital medicine, medical devices, and biopharma 2. Clinical Research Organizations (CROs) run trials. Regulatory consultants steer Food and Drug Administration (FDA) paths. They also guide European Medicines Agency (EMA) routes. Specialized recruiters hire biotech talent. Prospects include QuantHealth and Guardoc as they shift into product work and commercialization.

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